Quick answer

eGFR estimates how well kidneys filter, calculated from creatinine (or cystatin C) plus demographics. Above 60 with healthy urine is reassuring; staged declines below 60 define chronic kidney disease.

What is eGFR (Estimated Glomerular Filtration Rate)?

Rather than measuring clearance directly (inconvenient), equations estimate milliliters-per-minute filtration from surrogate markers. Staging follows KDIGO conventions: G1 ≥90 (normal-high), G2 60–89 (mildly reduced, often benign aging), G3a/b 45–59/30–44 (moderate), G4 15–29 (severe), G5 <15 (failure, dialysis conversations begin).

Typical reference interval: Healthy young adults typically 90–120 mL/min/1.73m²; interpret stages alongside albuminuria and trend.. Laboratories differ — the interval printed on YOUR report always governs.

If your eGFR (Estimated Glomerular Filtration Rate) is high

Common reasons eGFR (Estimated Glomerular Filtration Rate) runs above the reference interval:

  • Not pathological — supranormal filtration occurs in early diabetes and pregnancy — eventually taxing, currently fine
  • Body-builder creatinine distortion — equations assume average muscle; excess mass inflates apparent function

If your eGFR (Estimated Glomerular Filtration Rate) is low

Common reasons eGFR (Estimated Glomerular Filtration Rate) runs below the reference interval:

  • CKD staging — the number IS the stage when chronically reduced
  • Acute kidney injury — rapid falls differ completely from slow drifts — speed determines urgency
  • Hyperfiltration precursor states — obesity/hypertension/diabetes show supranormal then declining trajectories

Symptoms worth knowing

eGFR itself stays mute until advanced stages (G4): fatigue, poor appetite, metallic taste, itching, nocturia, fluid retention. Earlier detection relies entirely on testing — which is why diabetics and hypertensives get screened annually regardless of feeling.

What usually happens next

  1. Single mildly-reduced readings in elderly people often reflect normal aging — confirm persistence over 3+ months before staging CKD
  2. Pair with urine albumin-to-creatinine ratio: the combination (staging + albuminuria) predicts risk better than either
  3. Medication dose-adjustments kick in below certain thresholds — metformin, gabapentin, DOACs notably

Get your eGFR (Estimated Glomerular Filtration Rate) checked

These lab tests measure eGFR (Estimated Glomerular Filtration Rate) directly. Ordering online takes a few minutes and results arrive securely.

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Panels that include this value

eGFR (Estimated Glomerular Filtration Rate) appears as one line inside these broader panels — better value than ordering single markers alone:

Related result guides

Frequently asked questions about eGFR (Estimated Glomerular Filtration Rate) results

Should I panic about eGFR 58 at age 72?

Probably not — population norms drift downward with age, and 58 without proteinuria, hypertension, or progressive trend often represents expected senescence. Persistence, protein, and trajectory decide, not the snapshot.

Why did my eGFR jump from 55 to 75 between labs?

Creatinine-based estimation wobbles with hydration, meat meals, and muscle status. Cystatin-C-based eGFR confirms suspicious jumps.

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