Quick answer

A carbon monoxide blood test measures how much of your hemoglobin is bound to carbon monoxide instead of oxygen. A high level means carbon monoxide poisoning — a medical emergency — from sources like faulty heaters, car exhaust, or smoke inhalation.

What is Carbon Monoxide (CO)?

Carbon monoxide (CO) is an odorless, colorless gas that binds hemoglobin far more tightly than oxygen, starving the body of oxygen. The blood test measures carboxyhemoglobin (the percentage of hemoglobin carrying CO). Because CO poisoning can be life-threatening and its symptoms are easily mistaken for flu, testing is critical when exposure is suspected.

Typical reference interval: Normal levels are low — nonsmokers commonly under 2-3%, while smokers can run higher (up to around 10%) from chronic exposure. Symptomatic poisoning generally involves higher levels; any suspected exposure with symptoms is treated as an emergency regardless of the number.. Laboratories differ — the interval printed on YOUR report always governs.

If your Carbon Monoxide (CO) is high

Common reasons Carbon Monoxide (CO) runs above the reference interval:

  • Faulty heating or cooking appliances — gas furnaces, water heaters, and stoves can leak CO — a leading cause of home poisoning
  • Car exhaust or generators — running engines in enclosed spaces, including attached garages, raises exposure fast
  • Smoke inhalation from fires — fires produce CO as a major toxic component
  • Smoking — cigarettes deliver CO, so smokers have chronically higher levels
  • Occupational exposure — forklift and furnace work in enclosed spaces can expose workers

If your Carbon Monoxide (CO) is low

Common reasons Carbon Monoxide (CO) runs below the reference interval:

  • No exposure — a low level is the expected outcome for most people — the reassuring result
  • Non-smoker status — people who do not smoke generally run very low
  • Recent exposure timing — CO clears over hours once exposure ends, so timing of the test matters

Symptoms worth knowing

Carbon monoxide poisoning causes headache, dizziness, nausea, confusion, and fatigue — symptoms easily mistaken for the flu. Severe poisoning brings loss of consciousness and can be fatal. Because it is odorless, people often do not realize they are being exposed.

What usually happens next

  1. If CO poisoning is suspected, get to fresh air and call emergency services immediately — this is a medical emergency, not a wait-and-see result
  2. Treatment is high-flow oxygen, sometimes in a hyperbaric chamber, guided by medical professionals
  3. Find and fix the source — a qualified technician should inspect appliances, and CO detectors should be installed

Get your Carbon Monoxide (CO) checked

These lab tests measure Carbon Monoxide (CO) directly. Ordering online takes a few minutes and results arrive securely.

We may earn a commission when you order through partner links on the following pages. Educational information here never replaces advice from a qualified healthcare provider.

Related result guides

Frequently asked questions about Carbon Monoxide (CO) results

Can I test my carbon monoxide level if I feel fine?

Testing is most useful when exposure is suspected or symptoms are present. A normal level in a non-smoker is reassuring, but if you have a suspected source (faulty appliance, exhaust), fix the source regardless — prevention matters more than a single number.

Why do smokers have higher carbon monoxide levels?

Cigarette smoke contains carbon monoxide, so smokers carry a chronic burden of carboxyhemoglobin. It falls within hours of stopping. That is one reason smokers are advised to avoid additional CO sources.

Browse all lab tests

Looking for a specific test instead of a result explanation? Our full catalog covers hundreds of lab tests and panels.