Smith-Magenis syndrome

Smith-Magenis syndrome (SMS) is a complex genetic disorder characterized by variable intellectual deficit, sleep disturbance, craniofacial and skeletal anomalies, psychiatric disorders, and speech and motor delay.

What is Smith-Magenis syndrome?

Smith-Magenis syndrome is a medical condition. A condition is a disease, disorder, or abnormal state that affects the body or mind. This page provides educational information only and is not a diagnosis.

If you think you may have Smith-Magenis syndrome, speak with a qualified healthcare provider for evaluation and guidance.

Symptoms that may be associated with Smith-Magenis syndrome

AnxietyConductive hearing impairmentConstipationDeeply set eyeFailure to thriveGastroesophageal refluxGeneralized non-motor (absence) seizureHearing impairmentHoarse voiceIncreased body weightSeizure

When to seek medical care

Seek medical advice if you have symptoms that are severe, persistent, or affecting your daily life. Emergency care is needed for symptoms like chest pain, difficulty breathing, confusion, or severe weakness.