Muckle-Wells syndrome

An intermediate form of cryopyrin-associated periodic syndrome (CAPS) and is characterized by recurrent fever (with malaise and chills), recurrent urticaria-like skin rash, sensorineural deafness, general signs of inflammation (eye redness, headaches, arthralgia/myalgia) and potentially life-threatening secondary amyloidosis (AA type).

What is Muckle-Wells syndrome?

Muckle-Wells syndrome is a medical condition. A condition is a disease, disorder, or abnormal state that affects the body or mind. This page provides educational information only and is not a diagnosis.

If you think you may have Muckle-Wells syndrome, speak with a qualified healthcare provider for evaluation and guidance.

Symptoms that may be associated with Muckle-Wells syndrome

Abdominal painArthralgiaChronic fatigueConjunctival hyperemiaFeverHeadacheHearing impairmentMyalgiaProgressive sensorineural hearing impairmentRecurrent feverSkin rashUrticaria

When to seek medical care

Seek medical advice if you have symptoms that are severe, persistent, or affecting your daily life. Emergency care is needed for symptoms like chest pain, difficulty breathing, confusion, or severe weakness.