hereditary spastic paraplegia 12

Autosomal dominant spastic paraplegia type 12 is a pure form of hereditary spastic paraplegia characterized by a childhood- to adulthood-onset of slowly progressive lower limb spasticity and hyperreflexia of lower extremities, extensor plantar reflexes, distal sensory impairment, variable urinary dysfunction and pes cavus.

Also known as: RTN2 hereditary spastic paraplegia, SPG12, autosomal dominant spastic paraplegia type 12, hereditary spastic paraplegia caused by mutation in RTN2, hereditary spastic paraplegia type 12, spastic paraplegia 12

Category: General

What is hereditary spastic paraplegia 12?

hereditary spastic paraplegia 12 is a recognized medical condition. This page explains what it is, symptoms that may accompany it, and the lab tests healthcare providers sometimes use to investigate it. It is educational information only and is not a diagnosis.

If you think you may have hereditary spastic paraplegia 12, speak with a qualified healthcare provider for evaluation and guidance.

Symptoms that may be associated with hereditary spastic paraplegia 12

Chronic constipationDiplopiaDysphagiaLower limb muscle weaknessMyalgiaSeizureUrinary incontinence

When to seek medical care

Seek medical advice if you have symptoms that are severe, persistent, or affecting your daily life. Emergency care is needed for symptoms like chest pain, difficulty breathing, confusion, or severe weakness.