Hereditary fructose intolerance

Hereditary fructose intolerance (HFI) is an autosomal recessive disorder of fructose metabolism, resulting from a deficiency of hepatic fructose-1-phosphate aldolase activity and leading to gastrointestinal disorders and postprandial hypoglycemia following fructose ingestion. HFI is a benign condition when treated, but it is life-threatening and potentially fatal if left untreated.

What is Hereditary fructose intolerance?

Hereditary fructose intolerance is a medical condition. A condition is a disease, disorder, or abnormal state that affects the body or mind. This page provides educational information only and is not a diagnosis.

If you think you may have Hereditary fructose intolerance, speak with a qualified healthcare provider for evaluation and guidance.

Symptoms that may be associated with Hereditary fructose intolerance

Abdominal distentionAbdominal painConstipationDiarrheaFailure to thriveGastrointestinal hemorrhageJaundiceNauseaSeizureVomiting

When to seek medical care

Seek medical advice if you have symptoms that are severe, persistent, or affecting your daily life. Emergency care is needed for symptoms like chest pain, difficulty breathing, confusion, or severe weakness.